DNA origami lattices on silicon open new possibilities for large-scale nanofabrication

A dissertation study at the University of Jyväskylä (Finland) developed two-dimensional fishnet-like structures from DNA ...
AlphaGalileo

A single-site DNA–histone cross-link causes a global breakdown of nucleosome structure and function

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.
AlphaGalileo

Dissertation: DNA origami lattices on silicon open new possibilities for large-scale nanofabrication (Parikka)

A dissertation study at the University of Jyväskylä (Finland) developed two-dimensional fishnet-like structures from DNA origami for silicon surfaces ...

Mitochondrial enzyme's atomic-level structure reveals how it processes RNA

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular ...
C&EN

A trio of AI methods tackles enzyme design

RFdiffusion2, RFdiffusion3, and Riff-Diff each solve different structural problems in computational enzyme design ...
Morning Overview on MSN

Microscopic droplets reveal DNA’s hidden architecture

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

What Does Nuclear Radiation Actually Do To Your Body?

Ionizing nuclear radiation is an invisible killer that can destroy and corrupt your body on a molecular level, leading to a ...
C&EN

These archaea built a distinct genetic code to put pyrrolysine in proteins

There are few hard and fast rules in the study of life, but perhaps the closest we get is the central dogma of molecular biology: DNA is transcribed to RNA, which gets translated into proteins. The ...
Frontiers

Environmental DNA-based metabarcoding reveals a high animal biodiversity level within Red Sea mangrove beds

Introduction: Mangroves play a vital role in stabilizing coastlines, supporting biodiversity, and delivering essential ecosystem services. Methods: To assess animal biodiversity in Avicennia marina ...
C&EN

Single-Cell Super-Resolution Quantification of Oxidative DNA Damage via Aptamer-Assisted DNA-PAINT

College of Chemistry and Molecular Sciences, State Key Laboratory of Metabolism and Regulation in Complex Organisms, College of Life Sciences, Taikang Center for Life and Medical Sciences, Wuhan ...