There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be ...

The DNA is unwound and unzipped. The helix structure is unwound. Special molecules break the weak hydrogen bonds between bases, which are holding the two strands together. This process occurs at ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...