A study identified two key genes (CTNNA1 and BCL2L13) as suppressors in spread of colorectal cancer, revealing new strategies ...

Cancer is a leading cause of death worldwide, and among all cancers, colorectal cancer ranks second in mortality, responsible ...

A collaborative study led by biomedical researchers Chris Lengner and M. Andrés Blanco at the School of Veterinary Medicine at the University of Pennsylvania has identified two genes that suppress ...

The new knowledge could lead to the use by CBI of renewable microbes and plant cells from poplar trees and switchgrass (two non-edible plants that grow fast) for demonstrating the scaled-up industrial ...

Scientists used CRISPR to disable the NRF2 gene, restoring chemotherapy sensitivity in lung cancer cells and slowing tumor growth. The technique worked even when only a fraction of tumor cells were ...

Northwestern scientists have developed a new nanostructure that supercharges CRISPR’s ability to safely and efficiently enter cells, potentially unlocking its full power to treat genetic diseases. By ...

CRISPR has taken the bioengineering world by storm since its first introduction. From treating sickle cell diseases to creating disease-resistant crops, the technology continues to boast success on ...

Last August, KJ Muldoon was born with a potentially fatal genetic disorder. Just six months later, he received a Crispr treatment designed just for him. Muldoon has a rare disorder known as CPS1 ...

Creative Biogene's CRISPR library screening service is based on a multifaceted approach that includes designing personalized CRISPR libraries for specific gene families, cell lines, or disease models.

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...