Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

RFdiffusion2, RFdiffusion3, and Riff-Diff each solve different structural problems in computational enzyme design ...

An international research team at the University of Hong Kong has discovered a human protein known as ANKLE1, which is ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

The field of dermatology has witnessed remarkable progress in the prevention and treatment of skin diseases over the past ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

What are the skin concerns of a 40-year-old woman? Derms explain how skin changes as we get older, plus share healthy ...

Stem cells sent to the ISS return with signs of accelerated aging, revealing key risks for future space travel.

Summary: A new study shows that the DNA repair enzyme Polβ plays a vital role in protecting the developing brain from harmful mutations. Researchers found that without Polβ, insertion-deletion ...