A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Macrophages can forge synaptic-like links with muscle fibers, sending rapid calcium signals that accelerate regeneration. The finding reveals a fast, unexpected repair pathway with major therapeutic ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

Major Finding: The REPAIRome reveals how each human gene influences the outcomes of double-strand break repair. Approach: Genome-wide knockouts paired with insertion and deletion profiling establish a ...