CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study

A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...
EurekAlert!

CDT1 overexpression suppresses DNA replication and induces DNA damage, suggesting a mechanism for cancer development

A research group led by Drs. Shusuke Tada and Takashi Tsuyama at the Department of Molecular Biology, Faculty of ...

New Discovery Exposes the Hidden Weak Spot Cancer Uses to Survive DNA Damage

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

Newly Discovered DNA “Danger Zone” Could Change What We Know About Human Disease

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...
Medscape

The Future of Replication Stress and DNA Damage and Repair in Endometrial Cancer

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...