An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Tuberculosis (TB) is one of the oldest and deadliest infectious diseases we know. It commonly impacts the lungs, but can also affect other areas of the body like the spine, brain or kidneys.

Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...

When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

Researchers have analyzed a sample of DNA believed to belong to Adolf Hitler, which they say reveals the dictator of Nazi Germany had a genetic marker for a rare disorder that can delay puberty, ...

Our DNA is arranged into chromosomes that carry a kind of protective shield at their ends, called telomeres. These protective caps are crucial to the stability of chromosomes, and when telomeres ...

The NovaSeq X Plus is a half-ton machine that looks like an industrial freezer, with a big touchscreen on top and racks to hold cartridges of chemicals below. Its job is to simultaneously sequence 128 ...

Decades of research has viewed DNA as a sequence-based instruction manual; yet every cell in the body shares the same genes – so where is the language that writes the memory of cell identities?

1 Industrial Biotechnology Centre, School of Biosciences, University of Kent, Canterbury, United Kingdom 2 R&D Cell Engineering Group, Lonza Biologics, Chesterford Research Park, Saffron Walden, ...