High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...
More than 20 years ago, scientists at Pfizer touted the benefits of using enzymes in various steps in bioprocessing. In some situations, though, bioprocessors use the smallest proteins that can be ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Enzyme activation by cellular metabolites ...
1 School of Medicine, ShaoXing University, Shaoxing, Zhejiang Province, China 2 Department of Cardiology, Shaoxing People's Hospital, Shaoxing, Zhejiang, China Once considered passive carriers of ...
This study provides fundamental new knowledge into the role of reversible cysteine oxidation and reduction in protein kinase regulation. The data provide convincing evidence that intramolecular ...
As an efficient gene editing tool, the CRISPR/Cas9 system has been widely employed to investigate and regulate the biosynthetic pathways of active ingredients in medicinal plants. CRISPR technology ...
High–angiotensin-converting enzyme (ACE)-levels are associated with cardiovascular disease, but little is known about the regulation of its expression. To assess the molecular mechanisms regulating ...
Within the family of cell membrane lipids known as phosphoinositides and the kinase enzymes that regulate them, phosphoinositide 3-kinases (PI3Ks) have been cast in a starring role as scientists study ...
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