For decades, Arieh Warshel, USC Distinguished Professor of Chemistry and a 2013 Nobel laureate, has used computer simulations ...
Researchers in a recent breakthrough have identified hidden enzyme mutation behind the cases of dementia, thereby leading to ...
High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...
Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes ...
In adults with stage IIIb–IV chronic kidney disease, the constipation drug lubiprostone did not reduce gut-derived uremic ...
Cell death triggered by GPX4 loss was slowed in cell cultures and in mouse model using compounds that specifically inhibit ferroptosis.