Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

An investigation into cellular components in bacteria has unexpectedly uncovered a feature with relevance across many life ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Tuberculosis (TB) is one of the oldest and deadliest infectious diseases we know. It commonly impacts the lungs, but can also affect other areas of the body like the spine, brain or kidneys.

Scientists capture the most detailed 3D images of chromatin condensates, revealing how DNA packs tightly inside cells.

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

Tiny repeated stretches of DNA in your genome may quietly shape how your body works, how your brain develops and how you ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

This week in Science, Michael K. Rosen and 10 other members of a large collaboration at the Marine Biological Laboratory, the ...