Scientists from Duke-NUS Medical School and their international collaborators have developed a new computational tool that ...
When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ...
The human body experiences various health problems because of inflammation, which can lead to joint pain, heart disease and ...
CNDP enzymes—carnosinase-1 (CNDP1) and carnosinase-2 (CNDP2)—are zinc-dependent metalloproteinases central to the metabolism of carnosine and related histidine-containing dipeptides. By maintaining ...
Background Pathogenic mutations in genes encoding components of the Ras/mitogen-activated protein kinase (Ras-MAPK) pathway cause RASopathy. Here, we describe five unrelated patients with SLE carrying ...
MIAMI, July 31, 2025 (GLOBE NEWSWIRE) -- Pasithea Therapeutics Corp. (NASDAQ: KTTA) (“Pasithea” or the “Company”), a clinical-stage biotechnology company developing PAS-004, a next-generation ...
Skin aging manifests as structural degradation, functional decline, and heightened disease susceptibility. Central to this process is the overactivation of the mitogen-activated protein kinase (MAPK) ...
PAS-004 is being tested in a phase 1 trial for MAPK pathway-driven advanced solid tumors, with dosing initiated at 30 mg. The trial is multicenter, open-label, and dose-escalation, assessing safety, ...
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