Cancer involves more than just genetic mutations; it also involves structural failures. Consider a city where roads disappear, isolating communities from vital resources.

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

This toxin, called colibactin, is made by certain strains of E. coli and other microbes that naturally live in the human gut.

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

Professor Dongsheng Liu of Tsinghua University, Professor Ziyang Hao of Capital Medical University, and Researcher Yuanchen ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

For the first time, chemists have fully synthesized verticillin A, a notoriously complex fungal molecule with striking anticancer potential.

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of medications that fix tissue damage caused by heart attack, inflammatory ...