Mitochondrial enzyme's atomic-level structure reveals how it processes RNA

Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...

Zentalis Pharmaceuticals: Late Stage, Lots Of Cash, Crushed By The Market

Zentalis has taken a beating in 2025 to date, as the market continues to value their pipeline as a liability rather than an ...
Le Lézard

Ascletis' Oral Small Molecule GLP-1, ASC30, Demonstrated Placebo-Adjusted Weight Loss of 7.7% with Better Gastrointestinal Tolerability in Its 13-Week U.S. Phase II Study in ...

Ascletis Pharma Inc. (HKEX: 1672, "Ascletis") announces today positive topline results in its 13-week Phase II study evaluating ASC30, an oral small molecule GLP-1 receptor (GLP-1R) agonist for the ...
The Scientist

How Naloxone Blocks Opioids at the Molecular Level

Mapping how Narcan reverses opioid overdose can provide a molecular blueprint for developing more effective drugs against ...