Enzyme linked to myelin damage may hold key to neurodegenerative diseases

Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name. Cell migration ...

How CAR T-cell therapies target myeloma at the molecular level

In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR ...
UC San Diego Today

Scientists Uncover Key Driver of Treatment-Resistant Cancer

UC San Diego scientists discover enzyme responsible for scrambling cancer genomes; results could enable new treatments for ...
Scientific Research Publishing

Baldo, B.A. and Pham, N.H. (2020) Biologics: Monoclonal Antibodies for Non-Cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones. In: Baldo, B.A. and Pham, N.H ...

ABSTRACT: Chronic inflammatory cutaneous diseases, such as atopic dermatitis (AD) and psoriasis, are complex disorders influenced by immune dysregulation, various genetic factors, and more recently ...
gut.bmj

Porcine-derived pancreatic enzyme replacement therapy may be linked to chronic hepatitis E virus infection in cystic fibrosis lung transplant recipients

Objectives In high-income countries hepatitis E virus (HEV) is an uncommonly diagnosed porcine-derived zoonoses. After identifying disproportionate chronic HEV infections in persons with cystic ...
BioSpace

FDA Probing Patient Death Linked to Takeda’s Enzyme Replacement Therapy

The regulator has received reports that a group of patients treated with Adzynma had neutralizing antibodies against the protein the therapy replaces. The FDA is investigating adverse events, ...