This study provides useful insights into addressing the question of whether the prevalence of autoimmune disease could be driven by sex differences in the T cell receptor (TCR) repertoire, correlating ...

Dual RNA-sequencing enables simultaneous profiling of protein-coding and non-coding transcripts from two interacting organisms, an essential capability when physical separation is difficult, such as ...

RNA, or ribonucleic acid, carries instructions between DNA and an organism's protein-building machinery, acting as a messenger to turn genetic information into proteins. RNA can reveal which genes are ...

RNA sequencing (RNA-Seq) is a high-throughput sequencing approach that enables comprehensive quantification of transcriptomes at a genome-wide scale. As a result, RNA-Seq has become a routine ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

First, I'd like to thank you for developing Remora. It has been an invaluable tool for my direct RNA sequencing data analysis. I am currently using Remora to compare modified versus canonical RNA ...

What biological questions can single-molecule RNA sequencing help address that traditional methods cannot? How can these technologies be applied in your area of research, and what limitations might ...

aSchool of Basic Medical Sciences, Tsinghua University, 100084, Beijing, China bCentre for Life Sciences, Tsinghua University, 100084, Beijing, China cDepartment of Infectious Diseases, Peking Union ...