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CDT1 overexpression suppresses DNA replication and triggers DNA damage linked to cancer, finds study
A research group has demonstrated that overexpression of Cdc10-dependent transcript 1 (CDT1), a key regulator of DNA ...
A research group led by Drs. Shusuke Tada and Takashi Tsuyama at the Department of Molecular Biology, Faculty of ...
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...
Jennifer A. Surtees has long been dedicated to studying genome stability and boosting community involvement in research. With a new National Institutes of Health (NIH) grant, she’ll get to do both.
Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism. DNA, which stands for deoxyribonucleic ...
The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...
Whether it is a microbe, a rose, or a dolphin, any form of life gets its building and operating instructions from the molecule of life, DNA. DNA comprises the genes and chromosomes that govern the ...
Adenine was first discovered in 1885 by the German physiologist Albrecht Kossel. He isolated adenine from the pancreas of oxen and named it "adenine" derived from the Greek word "aden," meaning gland.
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