Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

With a rate of mutation 35 percent higher than random chance, this previously unknown weakness could be a major vector for ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

Figure 1. ANKLE1 senses mechanical tension in DNA and helps resolve DNA bridges connecting separating daughter nuclei. ANKLE1 ...

Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.

Bacteria are among the most diverse and ancient forms of life on Earth. Yet, much of what is known about them comes from a ...

Cells are not immortal, and that is a good thing. After a certain number of divisions, many human cells stop multiplying for ...

When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example DNA damage ...

Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which ...