Researchers discovered that a long-misunderstood protein plays a key role in helping chromosomes latch onto the right “tracks ...
An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...
An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...
Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells ...
With a rate of mutation 35 percent higher than random chance, this previously unknown weakness could be a major vector for ...
When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example, DNA damage ...
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
Figure 1. ANKLE1 senses mechanical tension in DNA and helps resolve DNA bridges connecting separating daughter nuclei. ANKLE1 ...
Myelodysplastic syndrome (MDS) arises from defective blood stem cells that progressively lose their normal functions.
A new study demonstrates that replicative senescence depends upon ATM kinase, and that high oxygen generates a hyperactive ...
Cells are not immortal, and that is a good thing. After a certain number of divisions, many human cells stop multiplying for ...