For the first time since coming back from injury, Ricky Pearsall was a productive player for the San Francisco 49ers. Against ...

Jason Logan breaks down his early 49ers vs. Colts predictions and explains why there's value backing the home underdog. Free ...

While the 49ers clinch a spot in the playoffs with a win over the Colts, San Francisco has another path towards the ...

The San Francisco 49ers are 10-4, and entering their Week 16 matchup against the Indianapolis Colts, they will have a chance ...

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Monday Night Football between San Francisco 49ers ...

The Indianapolis Colts were also 14.5-point underdogs in Week 15. They faced the Seattle Seahawks. It was Philip Rivers’ ...

San Francisco 49ers head coach Kyle Shanahan opens up about facing veteran quarterback Philip Rivers of the Indianapolis ...

Philip Rivers will remain the Colts' starting quarterback for their Week 16 "Monday Night Football" matchup with the 49ers, ...

After starting the season with a 10-4 record, the San Francisco 49ers take on the Indianapolis. Here's a look at the betting ...

Get the full 49ers practice and media schedule ahead of the Week 16 matchup vs. the Colts, including press conferences with ...

The San Francisco 49ers officially will face off against Philip Rivers in Week 16 against the Indianapolis Colts.

Meanwhile, the 49ers are set to get some much-needed reinforcements on run defense, and Ricky Pearsall's status for Week 16 ...