San Francisco 49ers wide receiver Ricky Pearsall is dealing with multiple injury concerns following Week 15’s win vs. the Titans.

The San Francisco 49ers could be getting some unexpected speed injected into their receiving corps late in the

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action. Both teams are watching injuries in the wake of Week 15 games.

The Tennessee Titans say the home of defensive tackle Jeffery Simmons was burglarized while he was on the road in San Francisco.

The San Francisco 49ers expectedly defeated the Tennessee Titans. A key reason why they were able to was thanks to the performances by a few players. As a resul

Two defensive stars were lost for the season. Their QB missed multiple games. Still, here are the 49ers are, a game out of the No. 1 seed.

In a press conference Monday, Indianapolis Colts Head Coach Shane Steichen confirmed that Philip Rivers will be the team's starting quarterback for their upcoming Monday Night Football game against the San Francisco 49ers.

Despite the missed opportunity to gain ground, the 49ers improved to 10-4 and remain firmly in the playoff hunt with three games left on the schedule. San Francisco will travel to face the Indianapolis Colts in Week 16 before closing the regular season with home games against the Chicago Bears and the Seahawks.