Thorax

Predictive capacity of paediatric nasal epithelial cells in sequential CFTR modulator therapy

Background CFTR modulators have transformed cystic fibrosis (CF) treatment, but individual responses vary even among patients with identical CFTR genotypes. This underscores the need for predictive ...
thorax.bmj

Shape-sensing robotic-assisted bronchoscopy with integrated mobile cone-beam CT for small nodules: results from the prospective multicentre CONFIRM study

Background The use of 3D imaging with navigation bronchoscopy has increased with the introduction of mobile cone-beam CT (mCBCT). Shape-sensing robotic-assisted bronchoscopy (ssRAB) integrated with ...
Thorax

Blood eosinophil-guided systemic corticosteroid duration in adults hospitalised for asthma exacerbation: a randomised, controlled, open-label, non-inferiority …

Objective Systemic corticosteroids for 5–7 days are standard care for asthma exacerbations, but the optimal duration and ...
Thorax

Maternal eating disorders and respiratory outcomes in childhood: findings from the EU Child Cohort Network

Background While maternal depression and anxiety have been linked to adverse childhood respiratory outcomes, the role of ...
Thorax

Multidisciplinary, non-pharmacological breathlessness intervention service for patients with moderately severe to severe COPD: a randomised controlled trial

Breathlessness intervention services (BIS), which coach patients to self-manage breathlessness using non-pharmacological ...
Thorax

Disproportionate impairment in diffusing capacity predicts pulmonary hypertension with an elevated pulmonary vascular resistance in COPD

Background Current guidelines for the evaluation of chronic obstructive pulmonary disease (COPD) do not recommend screening ...