Patients with ATTR-CM had significantly impaired global longitudinal strain and higher mechanical dispersion compared to their first-degree relatives who were not affected by the disease. Increased ...

Patients with ATTR‐CM who experienced an early improvement in left ventricular ejection fraction following cardiac resynchronization therapy implantation had a longer survival. New research shows that ...

A multidisciplinary approach is necessary for the deep phenotyping and proper clinical management of individuals with primary mitochondrial diseases. A large percentage of patients (60%) with primary ...

The treatment could potentially help patients reduce the use of glucocorticoids and immunosuppressants, the authors of the study said. The safety and efficacy of efgartigimod for the treatment of ...

The ODDS score showed strong predictive accuracy for 1-year transplant-free survival across varying levels of disease severity and oxygen needs. Researchers have devised a novel composite score that ...

The revisions include the addition of a boxed warning that describes the risk of serious hepatic injury and acute liver failure as well as possible fatal outcomes and the limitation of the use of the ...

Coramitug is well tolerated and leads to a statistically significant reduction in N-terminal pro-brain type natriuretic peptide (NT-proBNP)—a marker of disease progression in transthyretin-mediated ...

A pattern recognition approach takes into account factors like disease progression rate, whether the disease symptoms are symmetrical or asymmetrical, whether they are predominantly distal or proximal ...

Treated participants showed preservation of alveolar epithelial type II progenitor cells, which are essential for lung repair and regeneration. Inhaled LTI-03 has shown the potential to reduce lung ...

Rituximab showed a potential benefit on the long-term disease trajectory for MG, keeping disease activity and treatment burden low. The initial placebo-controlled portion of the trial showed the ...

The recurrence analysis found that the presence or absence of the IL36RN gene was not associated with recurrence. The use of biologics, particularly interleukin-36 (IL-36) inhibition, has resulted in ...