One person died and several others were injured in a multi-car crash on I-55 in south St. Louis early this morning. The crash ...

Dr. Craig Spiegel pleaded guilty to three federal charges over the illegal distribution scheme which started as early as 2014 ...

The Madison County Sheriff’s Office, along with the Fredericktown Police Department, Cherokee Pass Fire Department, Madison County Ambulance District and Madison County 911, helped the St. Louis ...

Police say that the incident was captured on store surveillance cameras, and the victim later identified the man in a lineup ...

Officials have been working to shore up the system since shortly after a tornado hit the city May 15 without the sirens ...

Rumors are claiming that the St. Louis Cardinals are likely to trade star third baseman Nolan Arenado during the offseason.

From fan-favorite Steinberg Skating Rink to a temporary wintertime rink near the Arch, here's where St. Louisans can enjoy ice time.

ST. LOUIS (AP) Amari McCottry scored 18 points as Saint Louis beat San Francisco 85-75 on Saturday. McCottry added five rebounds for the Billikens (9-1). Dion Brown added 14 points and 11 rebounds.

The casting team for Love Island USA, a well-known dating competition show, is "on the hunt for St. Louis singles" ahead of ...

City voters must decide every five years whether to keep the tax, which accounts for 36% of the government's general fund, ...

A 19-year-old is being accused of first-degree murder following a homicide that occurred in south St. Louis on Thursday.

A fast-moving weather system will slide through the region Saturday, bringing light snow mainly to northeastern Missouri and ...